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A Peptide-Embedded Trifluoromethyl Ketone Catalyst for Enantioselective Epoxidation

[Image: see text] The development of peptide-based oxidation catalysts that use a transiently generated dioxirane as the chemically active species is reported. The active catalyst is a chiral trifluoromethyl ketone (Tfk) with a pendant carboxylic acid that can be readily incorporated into a peptide....

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Autors principals: Romney, David K., Miller, Scott J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288446/
https://ncbi.nlm.nih.gov/pubmed/22315978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3000712
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