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Function-Oriented Investigations of a Peptide-Based Catalyst that Mediates Enantioselective Allylic Alcohol Epoxidation

We detail an investigation of a peptide-based catalyst 6 that is effective for the site- (>100:1:1) and enantioselective epoxidation (86% ee) of farnesol. Studies of the substrate scope exhibited by the catalyst are included, along with an exploration of optimized reaction conditions. Mechanistic...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Abascal, Nadia C., Lichtor, Phillip A., Giuliano, Michael W., Miller, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224318/
https://ncbi.nlm.nih.gov/pubmed/25386335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4SC01440E
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