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Genetic and Molecular Characterization of Uveal Melanoma Cell Lines

SUMMARY: The recent identification of frequent activating mutations in GNAQ or GNA11 in uveal melanoma provides an opportunity to better understand the pathogenesis of this melanoma subtype, and to develop rational therapeutics to target the cellular effects mediated by these mutations. Cell lines f...

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Détails bibliographiques
Auteurs principaux: Griewank, Klaus G., Yu, Xiaoxing, Khalili, Jahan, Sozen, M. Mert, Stempke-Hale, Katherine, Bernatchez, Chantale, Wardell, Seth, Bastian, Boris C., Woodman, Scott E.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288394/
https://ncbi.nlm.nih.gov/pubmed/22236444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2012.00971.x
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