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Genetic and Molecular Characterization of Uveal Melanoma Cell Lines

SUMMARY: The recent identification of frequent activating mutations in GNAQ or GNA11 in uveal melanoma provides an opportunity to better understand the pathogenesis of this melanoma subtype, and to develop rational therapeutics to target the cellular effects mediated by these mutations. Cell lines f...

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Detalhes bibliográficos
Main Authors: Griewank, Klaus G., Yu, Xiaoxing, Khalili, Jahan, Sozen, M. Mert, Stempke-Hale, Katherine, Bernatchez, Chantale, Wardell, Seth, Bastian, Boris C., Woodman, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288394/
https://ncbi.nlm.nih.gov/pubmed/22236444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2012.00971.x
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