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The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked By Prominent RNA Oxidation in Vulnerable Neurons

Although neuronal RNA oxidation is a prominent and established feature in age-associated neurodegenerative disorders such as Alzheimer disease (AD), oxidative damage to neuronal RNA in aging and in the transitional stages from normal elderly to the onset of AD has not been fully examined. In this st...

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Detaylı Bibliyografya
Asıl Yazarlar: Nunomura, Akihiko, Tamaoki, Toshio, Motohashi, Nobutaka, Nakamura, Masao, McKeel, Daniel W., Tabaton, Massimo, Lee, Hyoung-gon, Smith, Mark A., Perry, George, Zhu, Xiongwei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288284/
https://ncbi.nlm.nih.gov/pubmed/22318126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318248e614
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