Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

It is now established that oxidative stress is one of the earliest, if not the earliest, change that occurs in the pathogenesis of Alzheimer's disease (AD). Consistent with this, mild cognitive impairment (MCI), the clinical precursor of AD, is also characterized by elevations in oxidative stre...

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Detalhes bibliográficos
Main Authors: Smith, Mark A., Zhu, Xiongwei, Tabaton, Massimo, Liu, Gang, McKeel, Daniel W., Cohen, Mark L., Wang, Xinglong, Siedlak, Sandra L., Hayashi, Takaaki, Nakamura, Masao, Nunomura, Akihiko, Perry, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842004/
https://ncbi.nlm.nih.gov/pubmed/20061651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1239
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