Pivotal Role of Inosine Triphosphate Pyrophosphatase in Maintaining Genome Stability and the Prevention of Apoptosis in Human Cells

Pure nucleotide precursor pools are a prerequisite for high-fidelity DNA replication and the suppression of mutagenesis and carcinogenesis. ITPases are nucleoside triphosphate pyrophosphatases that clean the precursor pools of the non-canonical triphosphates of inosine and xanthine. The precise role...

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Hlavní autoři: Menezes, Miriam Rose, Waisertreiger, Irina S.-R., Lopez-Bertoni, Hernando, Luo, Xu, Pavlov, Youri I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288088/
https://ncbi.nlm.nih.gov/pubmed/22384212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032313
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