Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation

Canonical autophagy is positively regulated by the Beclin 1/phosphatidylinositol 3-kinase class III (PtdIns3KC3) complex that generates an essential phospholipid, phosphatidylinositol 3-phosphate (PtdIns(3)P), for the formation of autophagosomes. Previously, we identified the human WIPI protein fami...

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Detalles Bibliográficos
Autores principales: Mauthe, Mario, Jacob, Anke, Freiberger, Sandra, Hentschel, Katharina, Stierhof, York-Dieter, Codogno, Patrice, Proikas-Cezanne, Tassula
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2011
Materias:
Basic Research-Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288019/
https://ncbi.nlm.nih.gov/pubmed/22082875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17802
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