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Gene-based multiple trait analysis for exome sequencing data

The common genetic variants identified through genome-wide association studies explain only a small proportion of the genetic risk for complex diseases. The advancement of next-generation sequencing technologies has enabled the detection of rare variants that are expected to contribute significantly...

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Main Authors: Zhao, Jingyuan, Thalamuthu, Anbupalam
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287915/
https://ncbi.nlm.nih.gov/pubmed/22373189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S75
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