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Incorporating predicted functions of nonsynonymous variants into gene-based analysis of exome sequencing data: a comparative study
Next-generation sequencing has opened up new avenues for the genetic study of complex traits. However, because of the small number of observations for any given rare allele and high sequencing error, it is a challenge to identify functional rare variants associated with the phenotype of interest. Re...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287855/ https://ncbi.nlm.nih.gov/pubmed/22373178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S20 |
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