Old lessons learned anew: family-based methods for detecting genes responsible for quantitative and qualitative traits in the Genetic Analysis Workshop 17 mini-exome sequence data

Family-based study designs are again becoming popular as new next-generation sequencing technologies make whole-exome and whole-genome sequencing projects economically and temporally feasible. Here we evaluate the statistical properties of linkage analyses and family-based tests of association for t...

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Detalhes bibliográficos
Main Authors: Simpson, Claire L, Justice, Cristina M, Krishnan, Mera, Wojciechowski, Robert, Sung, Heejong, Cai, Jerry, Green, Tiffany, Lewis, Deyana, Behneman, Dana, Wilson, Alexander F, Bailey-Wilson, Joan E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287924/
https://ncbi.nlm.nih.gov/pubmed/22373393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S83
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