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Effects of genome-wide copy number variation on expression in mammalian cells

BACKGROUND: There is only a limited understanding of the relation between copy number and expression for mammalian genes. We fine mapped cis and trans regulatory loci due to copy number change for essentially all genes using a human-hamster radiation hybrid (RH) panel. These loci are called copy num...

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書誌詳細
主要な著者: Wang, Richard T, Ahn, Sangtae, Park, Christopher C, Khan, Arshad H, Lange, Kenneth, Smith, Desmond J
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287593/
https://ncbi.nlm.nih.gov/pubmed/22085887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-562
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