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Directed Mammalian Gene Regulatory Networks Using Expression and Comparative Genomic Hybridization Microarray Data from Radiation Hybrids

Meiotic mapping of quantitative trait loci regulating expression (eQTLs) has allowed the construction of gene networks. However, the limited mapping resolution of these studies has meant that genotype data are largely ignored, leading to undirected networks that fail to capture regulatory hierarchie...

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Detalhes bibliográficos
Main Authors: Ahn, Sangtae, Wang, Richard T., Park, Christopher C., Lin, Andy, Leahy, Richard M., Lange, Kenneth, Smith, Desmond J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690838/
https://ncbi.nlm.nih.gov/pubmed/19521529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000407
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