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An unstructured 5′-coding region of the prfA mRNA is required for efficient translation

Expression of virulence factors in the human bacterial pathogen Listeria monocytogenes is almost exclusively regulated by the transcriptional activator PrfA. The translation of prfA is controlled by a thermosensor located in the 5′-untranslated RNA (UTR), and is high at 37°C and low at temperatures...

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Detalhes bibliográficos
Main Authors: Loh, Edmund, Memarpour, Faranak, Vaitkevicius, Karolis, Kallipolitis, Birgitte H., Johansson, Jörgen, Sondén, Berit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287183/
https://ncbi.nlm.nih.gov/pubmed/22053088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr850
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