Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples

BACKGROUND: Duplication of chromosome 15q11-q13 (dup15q) accounts for approximately 3% of autism cases. Chromosome 15q11-q13 contains imprinted genes necessary for normal mammalian neurodevelopment controlled by a differentially methylated imprinting center (imprinting center of the Prader-Willi loc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Scoles, Haley A, Urraca, Nora, Chadwick, Samuel W, Reiter, Lawrence T, LaSalle, Janine M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287113/
https://ncbi.nlm.nih.gov/pubmed/22152151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-2-19
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki