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Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples
BACKGROUND: Duplication of chromosome 15q11-q13 (dup15q) accounts for approximately 3% of autism cases. Chromosome 15q11-q13 contains imprinted genes necessary for normal mammalian neurodevelopment controlled by a differentially methylated imprinting center (imprinting center of the Prader-Willi loc...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287113/ https://ncbi.nlm.nih.gov/pubmed/22152151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-2-19 |
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