New Insights into the Immunological Changes in IL-10-Deficient Mice during the Course of Spontaneous Inflammation in the Gut Mucosa

IL-10 is a regulatory cytokine that plays a major role in the homeostasis of the gut and this is illustrated by the fact that IL-10(−/−) mice develop spontaneous colitis. In this study, IL-10(−/−) mice were analyzed for immunological changes during colitis development. We found a reduced frequency o...

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Bibliographic Details
Main Authors: Gomes-Santos, Ana Cristina, Moreira, Thais Garcias, Castro-Junior, Archimedes Barbosa, Horta, Bernardo Coelho, Lemos, Luisa, Cruz, Deborah Nogueira, Guimarães, Mauro Andrade Freitas, Cara, Denise Carmona, McCafferty, Donna-Marie, Faria, Ana Maria Caetano
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287045/
https://ncbi.nlm.nih.gov/pubmed/22400037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/560817
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