New Insights into the Immunological Changes in IL-10-Deficient Mice during the Course of Spontaneous Inflammation in the Gut Mucosa

IL-10 is a regulatory cytokine that plays a major role in the homeostasis of the gut and this is illustrated by the fact that IL-10−/− mice develop spontaneous colitis. In this study, IL-10−/− mice were analyzed for immunological changes during colitis development. We found a reduced frequency of re...

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Главные авторы: Ana Cristina Gomes-Santos, Thais Garcias Moreira, Archimedes Barbosa Castro-Junior, Bernardo Coelho Horta, Luisa Lemos, Deborah Nogueira Cruz, Mauro Andrade Freitas Guimarães, Denise Carmona Cara, Donna-Marie McCafferty, Ana Maria Caetano Faria
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Limited 2012-01-01
Серии:Clinical and Developmental Immunology
Online-ссылка:http://dx.doi.org/10.1155/2012/560817
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