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Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation

Cutaneous malignant melanoma is considered one of the most deadly human cancers, based on both its penchant for metastatic spread and its typical resistance to currently available therapy. Long known to harbor oncogenic NRAS mutations, melanomas were more recently reported to be frequent bearers of...

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Main Authors: Mishra, PJ, Ha, L, Rieker, J, Sviderskaya, EV, Bennett, DC, Oberst, MD, Kelly, K, Merlino, G
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287039/
https://ncbi.nlm.nih.gov/pubmed/20118982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.521
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