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Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation
Cutaneous malignant melanoma is considered one of the most deadly human cancers, based on both its penchant for metastatic spread and its typical resistance to currently available therapy. Long known to harbor oncogenic NRAS mutations, melanomas were more recently reported to be frequent bearers of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287039/ https://ncbi.nlm.nih.gov/pubmed/20118982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.521 |
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