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Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains

Prion disease associated neurotoxicity is mainly attributed to PrP-scrapie (PrP(Sc)), the disease associated isoform of a normal protein, the prion protein (PrP(C)). Participation of other proteins and processes is suspected, but their identity and contribution to the pathogenic process is unclear....

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Bibliografiske detaljer
Main Authors: Singh, Ajay, Qing, Liuting, Kong, Qingzhong, Singh, Neena
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286598/
https://ncbi.nlm.nih.gov/pubmed/22182691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.12.012
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