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Alanine substitution scanning of pannexin1 reveals amino acid residues mediating ATP sensitivity
Pannexin1 is a prime candidate to represent an ATP release channel. The pannexin1 channel can be activated by extracellular ATP through purinergic receptors P2X7 or P2Y. Recent studies have shown that the Pannexin1 channel is inhibited by its own permeant ion, ATP, and also by P2X7 receptor agonists...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer Netherlands
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286540/ https://ncbi.nlm.nih.gov/pubmed/21987098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9263-6 |
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