Loading...

Alanine substitution scanning of pannexin1 reveals amino acid residues mediating ATP sensitivity

Pannexin1 is a prime candidate to represent an ATP release channel. The pannexin1 channel can be activated by extracellular ATP through purinergic receptors P2X7 or P2Y. Recent studies have shown that the Pannexin1 channel is inhibited by its own permeant ion, ATP, and also by P2X7 receptor agonists...

Full description

Saved in:
Bibliographic Details
Main Authors: Qiu, Feng, Wang, Junjie, Dahl, Gerhard
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286540/
https://ncbi.nlm.nih.gov/pubmed/21987098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9263-6
Tags: Add Tag
No Tags, Be the first to tag this record!