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Alanine substitution scanning of pannexin1 reveals amino acid residues mediating ATP sensitivity

Pannexin1 is a prime candidate to represent an ATP release channel. The pannexin1 channel can be activated by extracellular ATP through purinergic receptors P2X7 or P2Y. Recent studies have shown that the Pannexin1 channel is inhibited by its own permeant ion, ATP, and also by P2X7 receptor agonists...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Qiu, Feng, Wang, Junjie, Dahl, Gerhard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286540/
https://ncbi.nlm.nih.gov/pubmed/21987098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9263-6
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