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Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import

BACKGROUND: Integration of human immunodeficiency virus type 1 (HIV-1) into a host cell chromosome is an essential step under the control of the viral integrase (IN). Although this enzyme is necessary and sufficient to catalyze the integration reaction in vitro, cellular cofactors are involved in th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cribier, Alexandra, Ségéral, Emmanuel, Delelis, Olivier, Parissi, Vincent, Simon, Aurélie, Ruff, Marc, Benarous, Richard, Emiliani, Stéphane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286403/
https://ncbi.nlm.nih.gov/pubmed/22176773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-104
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