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Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection

BACKGROUND: HIV-1 replication requires integration of its reverse transcribed viral cDNA into a host cell chromosome. The DNA cutting and joining reactions associated to this key step are catalyzed by the viral protein integrase (IN). In infected cells, IN binds the viral cDNA, together with viral a...

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Bibliographische Detailangaben
Hauptverfasser: Gérard, Annabelle, Soler, Nicolas, Ségéral, Emmanuel, Belshan, Michael, Emiliani, Stéphane
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571920/
https://ncbi.nlm.nih.gov/pubmed/23369367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-13
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