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Specificity Protein 1 (Sp1) Oscillation Is Involved in Copper Homeostasis Maintenance by Regulating Human High-Affinity Copper Transporter 1 Expression

Copper is an essential micronutrient for cell growth but is toxic in excess. Copper transporter (Ctr1) plays an important role in regulating adequate copper levels in mammalian cells. We have shown previously that expression of the human high-affinity copper transporter (hCtr1) was transcriptionally...

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Auteurs principaux: Liang, Zheng D., Tsai, Wen-Bin, Lee, Mei-Yi, Savaraj, Niramol, Kuo, Macus Tien
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286298/
https://ncbi.nlm.nih.gov/pubmed/22172574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.076422
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