Human Cytochrome P450scc (CYP11A1) Catalyzes Epoxide Formation with Ergosterol

Cytochrome P450scc (P450scc) catalyzes the cleavage of the side chain of both cholesterol and the vitamin D(3) precursor, 7-dehydrocholesterol. The aim of this study was to test the ability of human P450scc to metabolize ergosterol, the vitamin D(2) precursor, and define the structure of the major p...

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Hauptverfasser: Tuckey, Robert C., Nguyen, Minh N., Chen, Jianjun, Slominski, Andrzej T., Baldisseri, Donna M., Tieu, Elaine W., Zjawiony, Jordan K., Li, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286270/
https://ncbi.nlm.nih.gov/pubmed/22106170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042515
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