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Inhibition of Genistein Glucuronidation by Bisphenol A in Human and Rat Liver Microsomes

Genistein is a natural phytoestrogen of the soybean, and bisphenol A (BPA) is a synthetic chemical used in the production of polycarbonate plastics. Both genistein and BPA disrupt the endocrine system in vivo and in vitro. Growing concerns of altered xenobiotic metabolism due to concomitant exposure...

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Autori principali: Coughlin, Janis L., Thomas, Paul E., Buckley, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286267/
https://ncbi.nlm.nih.gov/pubmed/22146138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042366
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