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Tannic Acid Down-Regulates the Angiotensin Type 1 Receptor Through a MAPK-Dependent Mechanism

In the present study, we investigated the effects of tannic acid (TA), a hydrolysable polyphenol, on angiotensin type 1 receptor (AT1R) expression in continuously passaged rat liver epithelial cells. Under normal conditions, exposure of cells to TA resulted in the down-regulation of AT1R-specific bi...

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Autors principals: Yesudas, Rekha, Gumaste, Upendra, Snyder, Russell, Thekkumkara, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286191/
https://ncbi.nlm.nih.gov/pubmed/22322600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1224
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