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Functional role of sodium glucose transporter in high glucose-mediated angiotensin type 1 receptor downregulation in human proximal tubule cells

Previously, we have demonstrated human angiotensin type 1 receptor (hAT(1)R) promoter architecture with regard to the effect of high glucose (25 mM)-mediated transcriptional repression in human proximal tubule epithelial cells (hPTEC; Thomas BE, Thekkumkara TJ. Mol Biol Cell 15: 4347–4355, 2004). In...

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Bibliographic Details
Main Authors: Yesudas, Rekha, Snyder, Russell, Abbruscato, Thomas, Thekkumkara, Thomas
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468487/
https://ncbi.nlm.nih.gov/pubmed/22647632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00651.2011
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