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Role of helix 44 of 16S rRNA in the fidelity of translation initiation

The molecular mechanisms that govern translation initiation to ensure accuracy remain unclear. Here, we provide evidence that the subunit-joining step of initiation is controlled in part by a conformational change in the 1408 region of helix h44. First, chemical probing of 30S initiation complexes f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qin, Daoming, Liu, Qi, Devaraj, Aishwarya, Fredrick, Kurt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285936/
https://ncbi.nlm.nih.gov/pubmed/22279149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031203.111
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