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Characterization of 16S rRNA mutations that decrease the fidelity of translation initiation

In bacteria, initiation of translation is kinetically controlled by factors IF1, IF2, and IF3, which work in conjunction with the 30S subunit to ensure accurate selection of the initiator tRNA (fMet-tRNA(fMet)) and the start codon. Here, we show that mutations G1338A and A790G of 16S rRNA decrease i...

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Detalhes bibliográficos
Main Authors: Qin, Daoming, Abdi, Nimo M., Fredrick, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080605/
https://ncbi.nlm.nih.gov/pubmed/17942743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.715307
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