Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses

Early in postnatal life, mossy fibres (MF), the axons of granule cells in the dentate gyrus, release GABA which is depolarizing and excitatory. Synaptic currents undergo spike-time dependent long-term depression (STD-LTD) regardless of the temporal order of stimulation (pre versus post and viceversa...

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Main Authors: Caiati, Maddalena D., Sivakumaran, Sudhir, Lanore, Frederic, Mulle, Christophe, Richard, Elodie, Verrier, Dany, Marsicano, Giovanni, Miles, Richard, Cherubini, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285903/
https://ncbi.nlm.nih.gov/pubmed/22368777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00285
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