PrP(C) Controls via Protein Kinase A the Direction of Synaptic Plasticity in the Immature Hippocampus

The cellular form of prion protein PrP(C) is highly expressed in the brain, where it can be converted into its abnormally folded isoform PrP(Sc) to cause neurodegenerative diseases. Its predominant synaptic localization suggests a crucial role in synaptic signaling. Interestingly, PrP(C) is developm...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Caiati, Maddalena D., Safiulina, Victoria F., Fattorini, Giorgia, Sivakumaran, Sudhir, Legname, Giuseppe, Cherubini, Enrico
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619229/
https://ncbi.nlm.nih.gov/pubmed/23407955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4149-12.2013
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