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PrP(C) Controls via Protein Kinase A the Direction of Synaptic Plasticity in the Immature Hippocampus

The cellular form of prion protein PrP(C) is highly expressed in the brain, where it can be converted into its abnormally folded isoform PrP(Sc) to cause neurodegenerative diseases. Its predominant synaptic localization suggests a crucial role in synaptic signaling. Interestingly, PrP(C) is developm...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Caiati, Maddalena D., Safiulina, Victoria F., Fattorini, Giorgia, Sivakumaran, Sudhir, Legname, Giuseppe, Cherubini, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619229/
https://ncbi.nlm.nih.gov/pubmed/23407955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4149-12.2013
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