Pro-Inflammatory wnt5a and Anti-Inflammatory sFRP5 Are Differentially Regulated by Nutritional Factors in Obese Human Subjects

BACKGROUND: Obesity is associated with macrophage infiltration of adipose tissue. These inflammatory cells affect adipocytes not only by classical cytokines but also by the secreted glycopeptide wnt5a. Healthy adipocytes are able to release the wnt5a inhibitor sFRP5. This protective effect, however,...

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Detalhes bibliográficos
Main Authors: Schulte, Dominik M., Müller, Nike, Neumann, Katrin, Oberhäuser, Frank, Faust, Michael, Güdelhöfer, Heike, Brandt, Burkhard, Krone, Wilhelm, Laudes, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285685/
https://ncbi.nlm.nih.gov/pubmed/22384249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032437
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