Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure

Elevated intraocular pressure (IOP) is the principal risk factor for glaucoma and results from excessive impedance of the fluid outflow from the eye. This abnormality likely originates from outflow pathway tissues such as the trabecular meshwork (TM), but the associated molecular etiology is poorly...

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書誌詳細
主要な著者: Wang, Wan-Heng, McNatt, Loretta G., Pang, Iok-Hou, Millar, J. Cameron, Hellberg, Peggy E., Hellberg, Mark H., Steely, H. Thomas, Rubin, Jeffrey S., Fingert, John H., Sheffield, Val C., Stone, Edwin M., Clark, Abbot F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2008
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242621/
https://ncbi.nlm.nih.gov/pubmed/18274669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33871
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