Genetic Ablation of Pannexin1 Protects Retinal Neurons from Ischemic Injury

Pannexin1 (Panx1) forms large nonselective membrane channel that is implicated in paracrine and inflammatory signaling. In vitro experiments suggested that Panx1 could play a key role in ischemic death of hippocampal neurons. Since retinal ganglion cells (RGCs) express high levels of Panx1 and are s...

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Detalhes bibliográficos
Main Authors: Dvoriantchikova, Galina, Ivanov, Dmitry, Barakat, David, Grinberg, Alexander, Wen, Rong, Slepak, Vladlen Z., Shestopalov, Valery I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285635/
https://ncbi.nlm.nih.gov/pubmed/22384122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031991
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