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Molecular pathways of pannexin1-mediated neurotoxicity

Pannexin1 (Panx1) forms non-selective membrane channels, structurally similar to gap junction hemichannels, and are permeable to ions, nucleotides, and other small molecules below 900 Da. Panx1 activity has been implicated in paracrine signaling and inflammasome regulation. Recent studies in differe...

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Autors principals: Shestopalov, Valery I., Slepak, Vladlen Z.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920106/
https://ncbi.nlm.nih.gov/pubmed/24575045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00023
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