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Early Priming Minimizes the Age-Related Immune Compromise of CD8(+) T Cell Diversity and Function
The elderly are particularly susceptible to influenza A virus infections, with increased occurrence, disease severity and reduced vaccine efficacy attributed to declining immunity. Experimentally, the age-dependent decline in influenza-specific CD8(+) T cell responsiveness reflects both functional c...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285595/ https://ncbi.nlm.nih.gov/pubmed/22383879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002544 |
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