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Early Priming Minimizes the Age-Related Immune Compromise of CD8(+) T Cell Diversity and Function

The elderly are particularly susceptible to influenza A virus infections, with increased occurrence, disease severity and reduced vaccine efficacy attributed to declining immunity. Experimentally, the age-dependent decline in influenza-specific CD8(+) T cell responsiveness reflects both functional c...

詳細記述

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書誌詳細
主要な著者: Valkenburg, Sophie A., Venturi, Vanessa, Dang, Thurston H. Y., Bird, Nicola L., Doherty, Peter C., Turner, Stephen J., Davenport, Miles P., Kedzierska, Katherine
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285595/
https://ncbi.nlm.nih.gov/pubmed/22383879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002544
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