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Complete subunit architecture of the proteasome regulatory particle
The proteasome is the major ATP-dependent protease in eukaryotic cells, but limited structural information strongly restricts a mechanistic understanding of its activities. The proteasome regulatory particle, consisting of the lid and base subcomplexes, recognizes and processes poly-ubiquitinated su...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285539/ https://ncbi.nlm.nih.gov/pubmed/22237024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10774 |
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