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Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains.

The display of proteins on the surface of phage offers a powerful means of selecting for rare genes encoding proteins with binding activities. Recently we found that antibody heavy and light chain variable (V) domains fused as a single polypeptide chain to a minor coat protein of filamentous phage f...

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Main Authors: Hoogenboom, H R, Griffiths, A D, Johnson, K S, Chiswell, D J, Hudson, P, Winter, G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1991
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC328552/
https://ncbi.nlm.nih.gov/pubmed/1908075
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