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Smad7 is Inactivated through a Direct Physical Interaction with the LIM Protein Hic-5/ARA55

We recently reported that hydrogen peroxide-inducible clone-5 (Hic-5, also named ARA55, androgen receptor-associated protein 55) can bind to the TGF-β signaling regulator Smad3, thereby inhibiting certain Smad3-dependent TGF-β responses. We now show that Hic-5 can also control TGF-β responses throug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Hui, Song, Kyung, Krebs, Tracy L., Yang, Jiayi, Danielpour, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285457/
https://ncbi.nlm.nih.gov/pubmed/18762808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.291
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