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Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells

We have previously reported that the expression of MAT2A (methionine adenosyltransferase 2A) is increased in human colon cancer and in colon cancer cells treated with IGF-1 (insulin-like growth factor-1), which was required for its mitogenic effect. The aim of the present study was to elucidate the...

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Autors principals: YANG, Heping, LI, Tony W. H., PENG, Jian, MATO, José M., LU, Shelly C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285440/
https://ncbi.nlm.nih.gov/pubmed/21406062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101754
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