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Molecular interactions and trafficking of influenza A virus polymerase proteins analyzed by specific monoclonal antibodies

The influenza polymerase complex composed of PA, PB1 and PB2, plays a key role in viral replication and pathogenicity. Newly synthesized components must be translocated to the nucleus, where replication and transcription of viral genomes take place. Previous studies suggest that while PB2 is translo...

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Detalhes bibliográficos
Main Authors: MacDonald, Leslie, Aggarwal, Shilpa, Bussey, Kendra A., Desmet, Emily A., Kim, Baek, Takimoto, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285403/
https://ncbi.nlm.nih.gov/pubmed/22325937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.01.015
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