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Structure of Minimal Tetratricopeptide Repeat Domain Protein Tah1 Reveals Mechanism of Its Interaction with Pih1 and Hsp90

Tah1 and Pih1 are novel Hsp90 interactors. Tah1 acts as a cofactor of Hsp90 to stabilize Pih1. In yeast, Hsp90, Tah1, and Pih1 were found to form a complex that is required for ribosomal RNA processing through their effect on box C/D small nucleolar ribonucleoprotein assembly. Tah1 is a minimal tetr...

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Detalhes bibliográficos
Main Authors: Jiménez, Beatriz, Ugwu, Francisca, Zhao, Rongmin, Ortí, Leticia, Makhnevych, Taras, Pineda-Lucena, Antonio, Houry, Walid A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285342/
https://ncbi.nlm.nih.gov/pubmed/22179618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.287458
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