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Phenotypic Detection of Clonotypic B Cells in Multiple Myeloma by Specific Immunoglobulin Ligands Reveals their Rarity in Multiple Myeloma

In multiple myeloma, circulating “clonotypic” B cells, that express the immunoglobulin rearrangement of the malignant plasma cell clone, can be indirectly detected by PCR. Their role as potential “feeder” cells for the malignant plasma cell pool remains controversial. Here we established for the fir...

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Autors principals: Trepel, Martin, Martens, Victoria, Doll, Christian, Rahlff, Janina, Gösch, Barbara, Loges, Sonja, Binder, Mascha
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285203/
https://ncbi.nlm.nih.gov/pubmed/22384124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031998
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