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Phenotypic Detection of Clonotypic B Cells in Multiple Myeloma by Specific Immunoglobulin Ligands Reveals their Rarity in Multiple Myeloma

In multiple myeloma, circulating “clonotypic” B cells, that express the immunoglobulin rearrangement of the malignant plasma cell clone, can be indirectly detected by PCR. Their role as potential “feeder” cells for the malignant plasma cell pool remains controversial. Here we established for the fir...

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Detalhes bibliográficos
Main Authors: Trepel, Martin, Martens, Victoria, Doll, Christian, Rahlff, Janina, Gösch, Barbara, Loges, Sonja, Binder, Mascha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285203/
https://ncbi.nlm.nih.gov/pubmed/22384124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031998
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