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Phenotypic Detection of Clonotypic B Cells in Multiple Myeloma by Specific Immunoglobulin Ligands Reveals their Rarity in Multiple Myeloma

In multiple myeloma, circulating “clonotypic” B cells, that express the immunoglobulin rearrangement of the malignant plasma cell clone, can be indirectly detected by PCR. Their role as potential “feeder” cells for the malignant plasma cell pool remains controversial. Here we established for the fir...

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Библиографические подробности
Главные авторы: Trepel, Martin, Martens, Victoria, Doll, Christian, Rahlff, Janina, Gösch, Barbara, Loges, Sonja, Binder, Mascha
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285203/
https://ncbi.nlm.nih.gov/pubmed/22384124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031998
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