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Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer

BACKGROUND: Delivery of a high concentration of anticancer drugs specifically to cancer cells remains the biggest challenge for the treatment of multidrug-resistant cancer. Poloxamers and D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) are known inhibitors of P-glycoprotein (P-gp). Mixed mi...

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Bibliografiske detaljer
Main Authors: Saxena, Vipin, Hussain, M Delwar
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284221/
https://ncbi.nlm.nih.gov/pubmed/22359450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S28745
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