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Imaging Protein Structure in Water at 2.7 nm Resolution by Transmission Electron Microscopy

We demonstrate an in situ transmission electron microscopy technique for imaging proteins in liquid water at room temperature. Liquid samples are loaded into a microfabricated environmental cell that isolates the sample from the vacuum with thin silicon nitride windows. We show that electron microgr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mirsaidov, Utkur M., Zheng, Haimei, Casana, Yosune, Matsudaira, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283772/
https://ncbi.nlm.nih.gov/pubmed/22385868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.009
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